A diastereoselective synthesis of pyrano fused coumarins via organocatalytic three-component reaction.
نویسندگان
چکیده
A new method for the synthesis of pyran fused coumarins by 3-bromo-4-hydroxycoumarins as cyclic α-halo ketones based on an organocatalyst assisted three-component tandem reaction is investigated. To the best of our knowledge, cyclic α-halo ketones have not yet been used for the synthesis of pyran fused coumarins.
منابع مشابه
Silica Sodium Carbonate as an Effective and Reusable Catalyst for the Three-Component Synthesis of Pyrano Coumarins
Silica sodium carbonate (SSC) has been used as a valuable silica-supported catalyst for the preparation of a range of known and novel pyrano coumarins via the three-component reactions of aryl aldehydes, active methylene compound (malononitrile or ethyl cyanoacetate), and hydroxycoumarin (5,7-dihydroxy-4-substituted coumarins or 4-hydroxycoumarin). The heterogeneous catalyst showed much the sam...
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 2 شماره
صفحات -
تاریخ انتشار 2013